Spinal Cord Compression: An Infrequent Complication of SAPHO Syndrome

©2015 Turkish League Against Rheumatism. All rights reserved. Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare group of sterile, inflammatory osteoarticular disorders classically associated with skin manifestations.1,2 The etiology is unknown, probably involves genetic, infectious, and immunological factors. The characteristic feature of the disease is found in the bone lesions, which typically involve the anterior chest wall and axial skeleton. Spondylodiscitis in SAPHO syndrome is sometimes difficult to distinguish from infectious spondylodiscitis. Nonsteroidal antiinflammatory drugs are usually the efficient treatment. Cases of destructive spondylitis leading to spinal cord compression are rarely reported in the literature.